Improved anti-tumor therapy based upon infectivity enhanced adenoviral delivery of RNA interference in ovarian carcinoma cell lines

BACKGROUND: Hec1 (Highly-Expressed-in-Cancer) has recently been shown to play an important role in the proper segregation of chromosomes during mitosis. Recently, an Adenovirus delivery system carrying RNA interference (RNAi) of Hec1 has been reported in a cervical adenocarcinoma model. Adenoviral d...

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Bibliographische Detailangaben
Hauptverfasser: Numnum, T Michael, Makhija, Sharmila, Lu, Baogen, Wang, Minghui, Rivera, Angel, Stoff-Khalili, Mariam, Alvarez, Ronald D, Zhu, Zeng Bian, Curiel, David T
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744403/
https://ncbi.nlm.nih.gov/pubmed/18061250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2007.08.096
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