Strategies to enhance transductional efficiency of adenoviral-based gene transfer to primary human fibroblasts and keratinocytes as a platform in dermal wounds

Genetically modified keratinocytes and fibroblasts are suitable for delivery of therapeutic genes capable of modifying the wound healing process. However, efficient gene delivery is a prerequisite for successful gene therapy of wounds. Whereas adenoviral vectors (Ads) exhibit superior levels of in v...

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Detalhes bibliográficos
Main Authors: Stoff, Alexander, Rivera, Angel A., Banerjee, N. S., Mathis, J. Michael, Espinosa-de-los-Monteros, Antonio, Le, Long P., De la Torre, Jorge I., Vasconez, Luis O., Broker, Thomas R., Richter, Dirk F., Stoff-Khalili, Mariam A., Curiel, David T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2203209/
https://ncbi.nlm.nih.gov/pubmed/17014674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1743-6109.2006.00168.x
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