Frequency and Evolution of Azole Resistance in Aspergillus fumigatus Associated with Treatment Failure

Azoles are the mainstay of oral therapy for aspergillosis. Azole resistance in Aspergillus has been reported infrequently. The first resistant isolate was detected in 1999 in Manchester, UK. In a clinical collection of 519 A. fumigatus isolates, the frequency of itraconazole resistance was 5%, a sig...

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Main Authors: Howard, Susan J., Cerar, Dasa, Anderson, Michael J., Albarrag, Ahmed, Fisher, Matthew C., Pasqualotto, Alessandro C., Laverdiere, Michel, Arendrup, Maiken C., Perlin, David S., Denning, David W.
格式: Artigo
語言:Inglês
出版: Centers for Disease Control and Prevention 2009
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744247/
https://ncbi.nlm.nih.gov/pubmed/19624922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3201/eid1507.090043
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