Frequency and Evolution of Azole Resistance in Aspergillus fumigatus Associated with Treatment Failure

Azoles are the mainstay of oral therapy for aspergillosis. Azole resistance in Aspergillus has been reported infrequently. The first resistant isolate was detected in 1999 in Manchester, UK. In a clinical collection of 519 A. fumigatus isolates, the frequency of itraconazole resistance was 5%, a sig...

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Detalhes bibliográficos
Main Authors: Howard, Susan J., Cerar, Dasa, Anderson, Michael J., Albarrag, Ahmed, Fisher, Matthew C., Pasqualotto, Alessandro C., Laverdiere, Michel, Arendrup, Maiken C., Perlin, David S., Denning, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: Centers for Disease Control and Prevention 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744247/
https://ncbi.nlm.nih.gov/pubmed/19624922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3201/eid1507.090043
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