Fully automated synthesis and initial PET evaluation of [(11)C]PBR28

Fully automated synthesis and initial PET evaluation of a TSPO radioligand, [(11)C]PBR28 (N-(2-[(11)C]methoxybenzyl)-N-(4-phenoxypyridin-3-yl)acetamide), are reported. These results facilitate the potential preclinical and clinical PET studies of [(11)C]PBR28 in animals and humans.

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Detalhes bibliográficos
Main Authors: Wang, Min, Yoder, Karmen K., Gao, Mingzhang, Mock, Bruce H., Xu, Xiao-Ming, Saykin, Andrew J., Hutchins, Gary D., Zheng, Qi-Huang
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743750/
https://ncbi.nlm.nih.gov/pubmed/19716298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2009.08.051
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