PARP1 gene variation and microglial activity on [(11)C]PBR28 PET in older adults at risk for Alzheimer's disease

Increasing evidence suggests that inflammation is one pathophysio-logical mechanism in Alzheimer's disease (AD). Recent studies have identifiedan association between the poly (ADP-ribose) polymerase 1 (PARP1) gene and AD. This gene encodes a protein that is involved in many biological functions...

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Publicat a:Multimodal Brain Image Anal (2013)
Autors principals: Kim, Sungeun, Nho, Kwangsik, Risacher, Shannon L., Inlow, Mark, Swaminathan, Shanker, Yoder, Karmen K., Shen, Li, West, John D, McDonald, Brenna C., Tallman, Eileen F., Hutchins, Gary D., Fletcher, James W., Farlow, Martin R., Ghetti, Bernardino, Saykin, Andrew J.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224281/
https://ncbi.nlm.nih.gov/pubmed/25383391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-319-02126-3_15
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