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Reversal of long-term dendritic spine alterations in Alzheimer disease models

Synapse loss is strongly correlated with cognitive impairment in Alzheimer's disease (AD). We have previously reported the loss of dendritic spines and the presence of dystrophic neurites in both the hippocampi of transgenic mice overexpressing amyloid precursor protein (APP) and in the human b...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Smith, Donna L., Pozueta, Julio, Gong, Bing, Arancio, Ottavio, Shelanski, Michael
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743726/
https://ncbi.nlm.nih.gov/pubmed/19805389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908706106
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