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Structure of the intact PPAR-γ–RXR-α nuclear receptor complex on DNA

Nuclear receptors are multi-domain transcription factors that bind to DNA elements from which they regulate gene expression. The peroxisome proliferator-activated receptors (PPARs) form heterodimers with the retinoid X receptor (RXR), and PPAR-γ has been intensively studied as a drug target because...

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Bibliografski detalji
Glavni autori: Chandra, Vikas, Huang, Pengxiang, Hamuro, Yoshitomo, Raghuram, Srilatha, Wang, Yongjun, Burris, Thomas P., Rastinejad, Fraydoon
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743566/
https://ncbi.nlm.nih.gov/pubmed/19043829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07413
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