Dose-response Curve Slope Sets Class-Specific Limits on Inhibitory Potential of Anti-HIV Drugs

Highly active antiretroviral therapy (HAART) can control HIV-1 replication1,2, but suboptimal treatment allows evolution of resistance and rebound viremia3–8. A comparative measure of antiviral activity under clinically relevant conditions would guide drug development and the selection of regimens t...

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Huvudupphovsmän: Shen, Lin, Peterson, Susan, Sedaghat, Ahmad R., McMahon, Moira A., Callender, Marc, Zhang, Haili, Zhou, Yan, Pitt, Eleanor, Anderson, Karen S., Acosta, Edward P., Siliciano, Robert F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743464/
https://ncbi.nlm.nih.gov/pubmed/18552857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1777
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