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The role of enhanced cutaneous IL-1β signaling in a rat tibia fracture model of complex regional pain syndrome

Tibia fracture in rats initiates a syndrome resembling the complex regional pain syndrome type I. Accumulating evidence indicates that IL-1β is involved in the modulation of nociceptive information and it acts as an intermediate inflammatory mediator via up-regulation of NGF. We hypothesized that IL...

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Main Authors: Li, Wenwu, Sabsovich, Ilya, Guo, Tian-Zhi, Zhao, Rong, Kingery, Wade S., Clark, J. David
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743308/
https://ncbi.nlm.nih.gov/pubmed/19473768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2009.04.033
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