Bisphosphonates inhibit pain, bone loss, and inflammation in a rat tibia fracture model of complex regional pain syndrome

BACKGROUND: Bisphosphonates are used to prevent the bone loss and fractures associated with osteoporosis, bone metastases, multiple myeloma, and osteogenis deformans. Distal limb fractures cause regional bone loss with cutaneous inflammation and pain in the injured limb that can develop into complex...

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Veröffentlicht in:Anesth Analg
Hauptverfasser: Wang, Liping, Guo, Tian-Zhi, Wei, Tzuping, Li, Wen-wu, Shi, Xiaoyou, Clark, J David, Kingery, Wade S
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5028129/
https://ncbi.nlm.nih.gov/pubmed/27636578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0000000000001518
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