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Comparison of amyloid plaque contrast generated by T(2)-, T(2)(*)-, and susceptibility-weighted imaging methods in transgenic mouse models of Alzheimer’s disease

One of the hallmark pathologies of Alzheimer’s disease (AD) is amyloid plaque deposition. Plaques appear hypointense on T(2)- and T(2)(*)-weighted MR images probably due to the presence of endogenous iron, but no quantitative comparison of various imaging techniques has been reported. We estimated t...

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Bibliographic Details
Main Authors: Chamberlain, Ryan, Reyes, Denise, Curran, Geoffrey L., Marjanska, Malgorzata, Wengenack, Thomas M., Poduslo, Joseph F., Garwood, Michael, Jack, Clifford R.
Format: Artigo
Language:Inglês
Published: 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743236/
https://ncbi.nlm.nih.gov/pubmed/19253386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.21951
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