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Targeting Vascular Amyloid in Arterioles of Alzheimer Disease Transgenic Mice with Amyloid Beta Protein Antibody-Coated Nanoparticles

The relevance of cerebral amyloid angiopathy (CAA) to the pathogenesis of Alzheimer disease (AD) and dementia in general emphasizes the importance of developing novel targeting approaches for detecting and treating cerebrovascular amyloid (CVA) deposits. We developed a nanoparticle-based technology...

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Detalhes bibliográficos
Publicado no:J Neuropathol Exp Neurol
Main Authors: Poduslo, Joseph F., Hultman, Kristi L., Curran, Geoffry L., Preboske, Gregory M., Chamberlain, Ryan, Marjańska, Małgorzata, Garwood, Michael, Jack, Clifford R., Wengenack, Thomas M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428546/
https://ncbi.nlm.nih.gov/pubmed/21760540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e318225038c
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