Targeting Vascular Amyloid in Arterioles of Alzheimer Disease Transgenic Mice with Amyloid Beta Protein Antibody-Coated Nanoparticles

The relevance of cerebral amyloid angiopathy (CAA) to the pathogenesis of Alzheimer disease (AD) and dementia in general emphasizes the importance of developing novel targeting approaches for detecting and treating cerebrovascular amyloid (CVA) deposits. We developed a nanoparticle-based technology...

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Bibliografiske detaljer
Udgivet i:J Neuropathol Exp Neurol
Main Authors: Poduslo, Joseph F., Hultman, Kristi L., Curran, Geoffry L., Preboske, Gregory M., Chamberlain, Ryan, Marjańska, Małgorzata, Garwood, Michael, Jack, Clifford R., Wengenack, Thomas M.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428546/
https://ncbi.nlm.nih.gov/pubmed/21760540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e318225038c
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