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In Vivo Visualization of Alzheimer’s Amyloid Plaques by MRI in Transgenic Mice Without a Contrast Agent

One of the cardinal pathologic features of Alzheimer’s disease (AD) is formation of senile, or amyloid, plaques. Transgenic mice have been developed that express one or more of the genes responsible for familial AD in humans. Doubly transgenic mice develop “human-like” plaques, providing a mechanism...

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Main Authors: Jack, Clifford R., Garwood, Michael, Wengenack, Thomas M., Borowski, Bret, Curran, Geoffrey L., Lin, Joseph, Adriany, Gregor, Grohn, Olli H.J., Grimm, Roger, Poduslo, Joseph F.
Format: Artigo
Jezik:Inglês
Izdano: 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744889/
https://ncbi.nlm.nih.gov/pubmed/15562496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.20266
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