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RIG-I is cleaved during picornavirus infection
The innate immune system senses RNA virus infections through membrane-bound Toll-like receptors or the cytoplasmic proteins RIG-I and MDA-5. RIG-I is believed to recognize the 5′-triphosphate present on many viral RNAs, and hence is important for sensing infections by paramyxoviruses, influenza viru...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2743091/ https://ncbi.nlm.nih.gov/pubmed/19628239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.06.045 |
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