Identification of avian RIG-I responsive genes during influenza infection

Ducks can survive infection with highly pathogenic avian influenza viruses that are lethal to chickens. We showed that the influenza detector, RIG-I, can initiate antiviral responses in ducks, but this gene is absent in chickens. We can reconstitute this pathway by transfecting chicken DF-1 embryoni...

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Bibliographic Details
Main Authors: Barber, Megan RW, Aldridge, Jerry R, Fleming-Canepa, Ximena, Wang, Yong-Dong, Webster, Robert G, Magor, Katharine E
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565471/
https://ncbi.nlm.nih.gov/pubmed/23220072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2012.10.038
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