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Identification of avian RIG-I responsive genes during influenza infection
Ducks can survive infection with highly pathogenic avian influenza viruses that are lethal to chickens. We showed that the influenza detector, RIG-I, can initiate antiviral responses in ducks, but this gene is absent in chickens. We can reconstitute this pathway by transfecting chicken DF-1 embryoni...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3565471/ https://ncbi.nlm.nih.gov/pubmed/23220072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2012.10.038 |
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