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Steroids Do Not Prevent Photoreceptor Degeneration in the Light-Exposed T4R Rhodopsin Mutant Dog Retina Irrespective of AP-1 Inhibition

PURPOSE: AP-1 has been proposed as a key intermediate linking exposure to light and photoreceptor cell death in rodent light damage models. Inhibition of AP-1 associated with steroid administration also prevents light damage. In this study the role of steroids in inhibiting AP-1 activation and/or in...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gu, Danian, Beltran, William A., Pearce-Kelling, Sue, Li, Zexiao, Acland, Gregory M., Aguirre, Gustavo D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742955/
https://ncbi.nlm.nih.gov/pubmed/19234347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-3111
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