LFA-1 Regulates CD8(+) T Cell Activation via T Cell Receptor-mediated and LFA-1-mediated Erk1/2 Signal Pathways

LFA-1 regulates T cell activation and signal transduction through the immunological synapse. T cell receptor (TCR) stimulation rapidly activates LFA-1, which provides unique LFA-1-dependent signals to promote T cell activation. However, the detailed molecular pathways that regulate these processes a...

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Bibliographic Details
Main Authors: Li, Dan, Molldrem, Jeffrey J., Ma, Qing
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Mechanisms of Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742865/
https://ncbi.nlm.nih.gov/pubmed/19483086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.002865
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