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Molecular Mechanism Underlying RAG1/RAG2 Synaptic Complex Formation
Two lymphoid cell-specific proteins, RAG1 and RAG2 (RAG), initiate V(D)J recombination by assembling a synaptic complex with recombination signal sequences (RSSs) abutting two different antigen receptor gene coding segments, and then introducing a DNA double strand break at the end of each RSS. Desp...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2742861/ https://ncbi.nlm.nih.gov/pubmed/19502597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.028977 |
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