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Regulatory Subunit I-controlled Protein Kinase A Activity Is Required for Apical Bile Canalicular Lumen Development in Hepatocytes

Signaling via cAMP plays an important role in apical cell surface dynamics in epithelial cells. In hepatocytes, elevated levels of cAMP as well as extracellular oncostatin M stimulate apical lumen development in a manner that depends on protein kinase A (PKA) activity. However, neither the identity...

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Detalhes bibliográficos
Main Authors: Wojtal, Kacper A., Diskar, Mandy, Herberg, Friedrich W., Hoekstra, Dick, van IJzendoorn, Sven C. D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742841/
https://ncbi.nlm.nih.gov/pubmed/19465483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.013599
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