Keratinocyte-derived Chemokine in Obesity: EXPRESSION, REGULATION, AND ROLE IN ADIPOSE MACROPHAGE INFILTRATION AND GLUCOSE HOMEOSTASIS

Obese adipose tissue (AT) is associated with chronic inflammation, and we hypothesized that the keratinocyte-derived chemokine (KC), the mouse ortholog of human interleukin-8, plays a role in obesity-mediated AT inflammation and the subsequent manifestation of insulin resistance. KC expression is in...

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Bibliographic Details
Main Authors: Neels, Jaap G., Badeanlou, Leylla, Hester, Kelly D., Samad, Fahumiya
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Metabolism and Bioenergetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742834/
https://ncbi.nlm.nih.gov/pubmed/19494115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.018556
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