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Fungal Zymosan and Mannan Activate the Cryopyrin Inflammasome

Some fungal species are opportunistic pathogens that can cause infection in people with compromised immune systems. Activation of caspase-1 and the subsequent secretion of mature interleukin (IL)-1β is a major signaling pathway of the innate immune system, but how yeasts induce caspase-1 activation...

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Main Authors: Lamkanfi, Mohamed, Malireddi, R. K. Subbarao, Kanneganti, Thirumala-Devi
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742822/
https://ncbi.nlm.nih.gov/pubmed/19509280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.023689
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