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Structure and Functional Implications of the Human Rad9-Hus1-Rad1 Cell Cycle Checkpoint Complex

Cellular DNA lesions are efficiently countered by DNA repair in conjunction with delays in cell cycle progression. Previous studies have demonstrated that Rad9, Hus1, and Rad1 can form a heterotrimeric complex (the 9-1-1 complex) that plays dual roles in cell cycle checkpoint activation and DNA repa...

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Autors principals: Xu, Min, Bai, Lin, Gong, Yong, Xie, Wei, Hang, Haiying, Jiang, Tao
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742809/
https://ncbi.nlm.nih.gov/pubmed/19535328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C109.022384
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