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Structure and Functional Implications of the Human Rad9-Hus1-Rad1 Cell Cycle Checkpoint Complex

Cellular DNA lesions are efficiently countered by DNA repair in conjunction with delays in cell cycle progression. Previous studies have demonstrated that Rad9, Hus1, and Rad1 can form a heterotrimeric complex (the 9-1-1 complex) that plays dual roles in cell cycle checkpoint activation and DNA repa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Xu, Min, Bai, Lin, Gong, Yong, Xie, Wei, Hang, Haiying, Jiang, Tao
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742809/
https://ncbi.nlm.nih.gov/pubmed/19535328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C109.022384
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