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Structure and Functional Implications of the Human Rad9-Hus1-Rad1 Cell Cycle Checkpoint Complex

Cellular DNA lesions are efficiently countered by DNA repair in conjunction with delays in cell cycle progression. Previous studies have demonstrated that Rad9, Hus1, and Rad1 can form a heterotrimeric complex (the 9-1-1 complex) that plays dual roles in cell cycle checkpoint activation and DNA repa...

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Библиографические подробности
Главные авторы: Xu, Min, Bai, Lin, Gong, Yong, Xie, Wei, Hang, Haiying, Jiang, Tao
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742809/
https://ncbi.nlm.nih.gov/pubmed/19535328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C109.022384
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