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Simulations of protein folding transition states using ψ-values

ψ-analysis has been used to identify inter-residue contacts in the transition state ensemble (TSE) of ubiquitin and other proteins. The magnitude of ψ depends on the degree to which an inserted bi-Histidine (biHis) metal ion binding site is formed in the TSE. A ψ equal to zero or one indicates that...

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Autors principals: Baxa, Michael C., Freed, Karl F., Sosnick, Tobin R.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742336/
https://ncbi.nlm.nih.gov/pubmed/19244613
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