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Circulating galectin-3 promotes metastasis by modifying MUC1 localization on cancer cell surface

Adhesion of circulating tumour cells to the blood vessel endothelium is a critical step in cancer metastasis. We show in this study that galectin-3, whose concentration is greatly increased in the circulation of cancer patients, increases cancer cell adhesion to macro- and micro-vascular endothelial...

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Detalhes bibliográficos
Main Authors: Zhao, Qicheng, Guo, Xiuli, Nash, Gerard B., Stone, Philip C., Hilkens, John, Rhodes, Jonathan M., Yu, Lu-Gang
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741610/
https://ncbi.nlm.nih.gov/pubmed/19690136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-1096
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