Valproic Acid and Other HDAC Inhibitors Induce Microglial Apoptosis and Attenuate Lipopolysaccharide- induced Dopaminergic Neurotoxicity

Valproic acid (VPA), a widely prescribed drug for seizures and bipolar disorder, has been shown to be an inhibitor of histone deacetylase (HDAC). Our previous study has demonstrated that VPA pretreatment reduces lipopolysaccharide (LPS)-induced dopaminergic (DA) neurotoxicity through the inhibition...

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Detaylı Bibliyografya
Asıl Yazarlar: Chen, Po See, Wang, Chao-Chuan, Bortner, Carl D., Peng, Giia-Sheun, Wu, Xuefei, Pang, Hao, Lu, Ru-Band, Gean, Po-Wu, Chuang, De-Maw, Hong, Jau-Shyong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2007
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741413/
https://ncbi.nlm.nih.gov/pubmed/17850978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2007.06.053
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