Formyl-methionyl-leucyl-phenylalanine–Induced Dopaminergic Neurotoxicity via Microglial Activation: A Mediator between Peripheral Infection and Neurodegeneration?

BACKGROUND: Parkinson disease (PD), a chronic neurodegenerative disease, has been proposed to be a multifactorial disorder resulting from a combination of environmental mechanisms (chemical, infectious, and traumatic), aging, and genetic deficits. Microglial activation is important in the pathogenes...

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Main Authors: Gao, Xi, Hu, Xiaoming, Qian, Li, Yang, Sufen, Zhang, Wei, Zhang, Dan, Wu, Xuefei, Fraser, Alison, Wilson, Belinda, Flood, Patrick M, Block, Michelle, Hong, Jau-Shyong
Format: Artigo
Sprog:Inglês
Udgivet: National Institute of Environmental Health Sciences 2008
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367670/
https://ncbi.nlm.nih.gov/pubmed/18470306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.11031
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