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Impairments in remote memory stabilization precede hippocampal synaptic and cognitive failures in 5XFAD Alzheimer mouse model

Although animal models of Alzheimer’s disease (AD) recapitulate β-amyloid-dependent hippocampal synaptic and cognitive dysfunctions, it is poorly understood how cortex-dependent remote memory stabilization following initial hippocampal coding is affected. Here, we systematically analyzed biophysical...

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Bibliografiske detaljer
Main Authors: Kimura, Ryoichi, Ohno, Masuo
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741400/
https://ncbi.nlm.nih.gov/pubmed/19026746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2008.10.006
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