Comparison of radiolabeled isatin analogs for imaging apoptosis with positron emission tomography

INTRODUCTION: Caspase-3 is one of the executioner caspases activated as a result of apoptosis. Radiolabeled isatins bind to caspase-3 with high affinity and are potential tracers for use with positron emission tomography to image apoptosis. We compared the ability of 2 novel radiolabeled isatins, [(...

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Main Authors: Chen, Delphine L., Zhou, Dong, Chu, Wenhua, Herrbrich, Phillip E., Jones, Lynne A., Rothfuss, Justin M, Engle, Jacquelyn T., Geraci, Marco, Welch, Michael J., Mach, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741397/
https://ncbi.nlm.nih.gov/pubmed/19647171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2009.03.008
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