Discovery of Escherichia coli methionyl-tRNA synthetase mutants for efficient labeling of proteins with azidonorleucine in vivo

Incorporation of noncanonical amino acids into cellular proteins often requires engineering new aminoacyl-tRNA synthetase activity into the cell. A screening strategy that relies on cell-surface display of reactive amino acid side-chains was used to identify a diverse set of methionyl-tRNA synthetas...

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Detaylı Bibliyografya
Asıl Yazarlar: Tanrikulu, I. Caglar, Schmitt, Emmanuelle, Mechulam, Yves, Goddard, William A., Tirrell, David A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2009
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741243/
https://ncbi.nlm.nih.gov/pubmed/19706454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905735106
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