Alternative-Splicing in the Exon-10 Region of GABA(A) Receptor β(2) Subunit Gene: Relationships between Novel Isoforms and Psychotic Disorders

BACKGROUND: Non-coding single nucleotide polymorphisms (SNPs) in GABRB2, the gene for β(2)-subunit of gamma-aminobutyric acid type A (GABA(A)) receptor, have been associated with schizophrenia (SCZ) and quantitatively correlated to mRNA expression and alternative splicing. METHODS AND FINDINGS: Expr...

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Autori principali: Zhao, Cunyou, Xu, Zhiwen, Wang, Feng, Chen, Jianhuan, Ng, Siu-Kin, Wong, Pak-Wing, Yu, Zhiliang, Pun, Frank W., Ren, Lihuan, Lo, Wing-Sze, Tsang, Shui-Ying, Xue, Hong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741204/
https://ncbi.nlm.nih.gov/pubmed/19763268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006977
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