A Recombination Hotspot in a Schizophrenia-Associated Region of GABRB2

BACKGROUND: Schizophrenia is a major disorder with complex genetic mechanisms. Earlier, population genetic studies revealed the occurrence of strong positive selection in the GABRB2 gene encoding the β(2) subunit of GABA(A) receptors, within a segment of 3,551 bp harboring twenty-nine single nucleot...

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Autores principales: Ng, Siu-Kin, Lo, Wing-Sze, Pun, Frank W., Zhao, Cunyou, Yu, Zhiliang, Chen, Jianhuan, Tong, Ka-Lok, Xu, Zhiwen, Tsang, Shui-Ying, Yang, Qiang, Yu, Weichuan, Nimgaonkar, Vishwajit, Stöber, Gerald, Harano, Mutsuo, Xue, Hong
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833194/
https://ncbi.nlm.nih.gov/pubmed/20221451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009547
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