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IgE-Mediated Allergen Gene Vaccine Platform Targeting Human Antigen Presenting Cells Via High Affinity IgE Receptor

BACKGROUND: Treatment of IgE-mediated food allergy with standard protein-based allergen immunotherapy has proven both unsuccessful and hazardous. Allergen gene vaccination represents a promising alternate, but difficulties in gene targeting and expression in antigen presenting cells represent a majo...

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Detalhes bibliográficos
Main Authors: Behnecke, Anne, Li, Wei, Chen, Ling, Saxon, Andrew, Zhang, Ke
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741176/
https://ncbi.nlm.nih.gov/pubmed/19423156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2009.03.020
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