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Blocking allergic reaction through targeting surface-bound IgE with low affinity anti-IgE antibodies

Allergic disorders now become a major worldwide public health issue but the effective treatment options remain limited. We report a novel approach to block allergic reactivity by targeting the surface-bound IgE of the allergic effector cells via low affinity anti-human IgE antibodies with dissociati...

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Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Zhang, Ke, Liu, Jeffrey, Truong, Thao, Zukin, Elyssa, Chen, Wendy, Saxon, Andrew
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685210/
https://ncbi.nlm.nih.gov/pubmed/28396318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1602022
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