A targeted neuroglial reporter line generated by homologous recombination in human embryonic stem cells

In this study we targeted Olig2, a basic helix-loop-helix transcription factor that plays an important role in motoneuron and oligodendrocyte development, in human embryonic stem cell (hESC) line BG01 by homologous recombination. One allele of Olig2 locus was replaced by a GFP cassette with a target...

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Detalhes bibliográficos
Main Authors: Xue, Haipeng, Wu, Sen, Papadeas, Sophia T., Spusta, Steve, Swistowska, Anna Maria, MacArthur, Chad C., Mattson, Mark P., Maragakis, Nicholas J., Capecchi, Mario R., Rao, Mahendra S., Zeng, Xianmin, Liu, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741170/
https://ncbi.nlm.nih.gov/pubmed/19544414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.129
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