Adaptable Molecular Interactions Guide Phosphorylation of the SR Protein ASF/SF2 By SRPK1

The SR protein ASF/SF2, an essential splicing factor, contains two functional modules consisting of tandem RNA recognition motifs (RRM1-RRM2) and a C-terminal arginine-serine repeat region (RS domain). The serine protein kinase SRPK1 phosphorylates the RS domain at multiple serines using a direction...

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Bibliographic Details
Main Authors: Hagopian, Jonathan C., Ma, Chen-Ting, Meade, Bryan R., Albuquerque, Claudio P., Ngo, Jacky C., Ghosh, Gourisankar, Jennings, Patricia A., Fu, Xiang-Dong, Adams, Joseph A.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741138/
https://ncbi.nlm.nih.gov/pubmed/18687337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.07.055
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