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Mechanism of Dephosphorylation of the SR Protein ASF/SF2 By Protein Phosphatase 1

SR proteins are essential splicing factors whose function is controlled by multi-site phosphorylation of a C-terminal domain rich in arginine-serine repeats (RS domain). The protein kinase SRPK1 has been shown to polyphosphorylate the N-terminal portion of the RS domain (RS1) of the SR protein ASF/S...

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Bibliografski detalji
Glavni autori: Ma, Chen-Ting, Ghosh, Gourisankar, Fu, Xiang-Dong, Adams, Joseph A.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994579/
https://ncbi.nlm.nih.gov/pubmed/20826166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.08.024
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