Učitavanje...
Catalytic and ligand-binding characteristics of Plasmodium falciparum serine hydroxymethyltransferase
The plant-like, bifunctional dihydrofolate reductase-thymidylate synthase (DHFR-TS) from malaria parasites has been a good target for drug development. Dihydrofolate reductase (DHFR) is inhibited by clinically established antimalarials, pyrimethamine and cycloguanil. Thymidylate synthase (TS) is the...
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| Glavni autori: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2741015/ https://ncbi.nlm.nih.gov/pubmed/19591883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2009.06.011 |
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