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TGF-β signaling deficient fibroblasts enhance Hepatocyte Growth Factor signaling in mammary carcinoma cells to promote scattering and invasion
Fibroblasts are major cellular components of the tumor microenvironment, regulating tumor cell behavior in part through secretion of extracellular matrix proteins, growth factors and angiogenic factors. In previous studies, conditional deletion of the type II TGF-β receptor in fibroblasts (Tgfbr2(Fs...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2740918/ https://ncbi.nlm.nih.gov/pubmed/18922968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-07-2203 |
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