Caricamento...
EDEM1 recognition and delivery of misfolded proteins to the SEL1L-containing ERAD complex
Terminally misfolded or unassembled secretory proteins are retained in the endoplasmic reticulum (ER) and subsequently cleared by the ER-associated degradation (ERAD) pathway. The degradation of ERAD substrates involves mannose trimming of N-linked glycans, however the mechanisms of substrate recogn...
Salvato in:
| Autori principali: | , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2740909/ https://ncbi.nlm.nih.gov/pubmed/19524542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.05.018 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|