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Integrin β3 Leu33Pro polymorphism increases BRCA1‐associated ovarian cancer risk
Integrins are heterodimeric transmembrane glycoproteins that function as key adhesion and cell signalling receptors. A functional polymorphism in the integrin β3 subunit encoded by the ITGB3 gene, Leu33Pro, has been shown to modify a variety of traits of β3‐expressing cells. To analyse the role of t...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BMJ Group
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2740893/ https://ncbi.nlm.nih.gov/pubmed/17220212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2006.047498 |
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