Integrin β3 Leu33Pro polymorphism increases BRCA1‐associated ovarian cancer risk

Integrins are heterodimeric transmembrane glycoproteins that function as key adhesion and cell signalling receptors. A functional polymorphism in the integrin β3 subunit encoded by the ITGB3 gene, Leu33Pro, has been shown to modify a variety of traits of β3‐expressing cells. To analyse the role of t...

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Detalhes bibliográficos
Main Authors: Jakubowska, Anna, Gronwald, Jacek, Menkiszak, Janusz, Górski, Bohdan, Huzarski, Tomasz, Byrski, Tomasz, Edler, Lutz, Lubiński, Jan, Scott, Rodney J, Hamann, Ute
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2007
Assuntos:
Letter to JMG
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740893/
https://ncbi.nlm.nih.gov/pubmed/17220212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2006.047498
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