Ovarian cancer risk in Polish BRCA1 mutation carriers is not associated with the prohibitin 3' untranslated region polymorphism

BACKGROUND: The variable penetrance of ovarian cancer in BRCA1 mutation carriers suggests that other genetic or environmental factors modify disease risk. The C to T transition in the 3' untranslated region of the prohibitin (PHB) gene alters mRNA function and has recently been shown to be asso...

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Autors principals: Jakubowska, Anna, Gronwald, Jacek, Menkiszak, Janusz, Górski, Bohdan, Huzarski, Tomasz, Byrski, Tomasz, Benner, Axel, Lubiński, Jan, Scott, Rodney J, Hamann, Ute
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364631/
https://ncbi.nlm.nih.gov/pubmed/18397521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-90
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