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Treatment of Influenza A (H1N1) Virus Infections in Mice and Ferrets with Cyanovirin-N
Cyanovirin-N (CV-N), a protein derived from Nostoc ellipsosporum, neutralizes influenza virus infectivity by binding to specific high-mannose oligosaccharides (oligomannose-8 and -9) at glycosylation sites on the viral hemagglutinin HA1 subunit. Mouse-adapted viruses lose sensitivity to CV-N due to...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2740641/ https://ncbi.nlm.nih.gov/pubmed/18601954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2008.06.003 |
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