Alternative Translation Initiation Generates Cytoplasmic Sheep Prion Protein

Cytoplasmic localization of the prion protein (PrP) has been observed in different species and cell types. We have investigated this poorly understood phenomenon by expressing fusion proteins of sheep prion protein and green fluorescent protein ((GFP)PrP) in N2a cells, with variable sequence context...

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Main Authors: Lund, Christoffer, Olsen, Christel M., Skogtvedt, Susan, Tveit, Heidi, Prydz, Kristian, Tranulis, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Protein Synthesis, Post-Translational Modification, and Degradation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740592/
https://ncbi.nlm.nih.gov/pubmed/19451655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.003566
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