The Cytoplasmic Peptidase DPP9 Is Rate-limiting for Degradation of Proline-containing Peptides

Protein degradation is an essential process that continuously takes place in all living cells. Regulated degradation of most cellular proteins is initiated by proteasomes, which produce peptides of varying length. These peptides are rapidly cleaved to single amino acids by cytoplasmic peptidases. Pr...

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Detalhes bibliográficos
Main Authors: Geiss-Friedlander, Ruth, Parmentier, Nicolas, Möller, Ulrike, Urlaub, Henning, Van den Eynde, Benoit J., Melchior, Frauke
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Protein Synthesis, Post-Translational Modification, and Degradation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785648/
https://ncbi.nlm.nih.gov/pubmed/19667070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.041871
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