Multimerization and DNA Binding Properties of INI1/hSNF5 and Its Functional Significance

INI1/hSNF5/BAF47/SMARCB1 is an HIV-1 integrase (IN)-binding protein that modulates viral replication in multiple ways. A minimal IN-binding domain of INI1, S6 (amino acids 183–294), transdominantly inhibits late events, and down-modulation of INI1 stimulates early events of HIV-1 replication. INI1 b...

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Bibliografiske detaljer
Main Authors: Das, Supratik, Cano, Jennifer, Kalpana, Ganjam V.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
DNA: Replication, Repair, Recombination, and Chromosome Dynamics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740416/
https://ncbi.nlm.nih.gov/pubmed/19398554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808141200
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