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Structure and function of the 5’→3’ exoribonuclease Rat1 and its activating partner Rai1

The 5’→3’ exoribonucleases (XRNs) comprise a large family of conserved enzymes in eukaryotes with crucial functions in RNA metabolism and RNA interference1–5. XRN2, or Rat1 in yeast6, functions primarily in the nucleus and also plays an important role in transcription termination by RNA polymerase I...

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Detalhes bibliográficos
Main Authors: Xiang, Song, Cooper-Morgan, Amalene, Jiao, Xinfu, Kiledjian, Megerditch, Manley, James L., Tong, Liang
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739979/
https://ncbi.nlm.nih.gov/pubmed/19194460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07731
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